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The Fix

pip install urllib3==1.25

Based on closed urllib3/urllib3 issue #1537 · PR/commit linked

Production note: Most teams hit this during upgrades or environment changes. Roll out with a canary and smoke critical endpoints (health, OpenAPI/docs) before 100%.

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@@ -22,6 +22,14 @@ dev (master) ``urllib3[brotli]`` extra. (Pull #1532) +* Add TLSv1.3 support to CPython, pyOpenSSL, and SecureTransport ``SSLContext`` + implementations. (Pull #1496) +
repro.py
asn1crypto==0.24.0 certifi==2018.11.29 cryptography==2.5 ddt==1.2.0 idna==2.8 pyOpenSSL==19.0.0 requests==2.21.0 requests-unixsocket==0.1.5 trustme==0.5.0 urllib3==1.24.1
verify
Re-run the minimal reproduction on your broken version, then apply the fix and re-run.
fix.md
Option A — Upgrade to fixed release\npip install urllib3==1.25\nWhen NOT to use: This fix is not applicable if using unsupported versions of OpenSSL or Python.\n\n

Why This Fix Works in Production

  • Trigger: OpenSSL.SSL.Error raised with invalid client cert and cryptography 2.5
  • Mechanism: Add support for TLS 1.3 to all HTTPSConnection implementations, resolving issues with OpenSSL errors when using invalid client certificates.
  • Why the fix works: Add support for TLS 1.3 to all HTTPSConnection implementations, resolving issues with OpenSSL errors when using invalid client certificates. (first fixed release: 1.25).
Production impact:
  • If left unfixed, the same config can fail only in production (env differences), causing startup failures or partial feature outages.

Why This Breaks in Prod

  • Shows up under Python 3.7.2 in real deployments (not just unit tests).
  • Production symptom (often without a traceback): OpenSSL.SSL.Error raised with invalid client cert and cryptography 2.5

Proof / Evidence

  • GitHub issue: #1537
  • Fix PR: https://github.com/urllib3/urllib3/pull/1496
  • First fixed release: 1.25
  • Reproduced locally: No (not executed)
  • Last verified: 2026-02-09
  • Confidence: 0.95
  • Did this fix it?: Yes (upstream fix exists)
  • Own content ratio: 0.66

Discussion

High-signal excerpts from the issue thread (symptoms, repros, edge-cases).

“This script replicates the issue”
@jaraco · 2019-02-05 · source
“I'm almost positive this is post-handshake authentication of client certificates.”
@sethmlarson · 2019-02-06 · source

Failure Signature (Search String)

  • OpenSSL.SSL.Error raised with invalid client cert and cryptography 2.5
  • In requests/requests#4961, I stumbled onto an issue where it appears that in the right scenario, OpenSSL errors are raised from
Copy-friendly signature
signature.txt
Failure Signature ----------------- OpenSSL.SSL.Error raised with invalid client cert and cryptography 2.5 In requests/requests#4961, I stumbled onto an issue where it appears that in the right scenario, OpenSSL errors are raised from `urllib.connectionpool.HTTPConnectionPool._make_request`. It happens with these deps

Error Message

Signature-only (no traceback captured)
error.txt
Error Message ------------- OpenSSL.SSL.Error raised with invalid client cert and cryptography 2.5 In requests/requests#4961, I stumbled onto an issue where it appears that in the right scenario, OpenSSL errors are raised from `urllib.connectionpool.HTTPConnectionPool._make_request`. It happens with these deps

Minimal Reproduction

repro.py
asn1crypto==0.24.0 certifi==2018.11.29 cryptography==2.5 ddt==1.2.0 idna==2.8 pyOpenSSL==19.0.0 requests==2.21.0 requests-unixsocket==0.1.5 trustme==0.5.0 urllib3==1.24.1

Environment

  • Python: 3.7.2

What Broke

Users experience SSL errors when making HTTPS requests with invalid client certificates.

Fix Options (Details)

Option A — Upgrade to fixed release Safe default (recommended)

pip install urllib3==1.25

When NOT to use: This fix is not applicable if using unsupported versions of OpenSSL or Python.

Use when you can deploy the upstream fix. It is usually lower-risk than long-lived workarounds.

Fix reference: https://github.com/urllib3/urllib3/pull/1496

First fixed release: 1.25

Last verified: 2026-02-09. Validate in your environment.

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When NOT to Use This Fix

  • This fix is not applicable if using unsupported versions of OpenSSL or Python.

Verify Fix

verify
Re-run the minimal reproduction on your broken version, then apply the fix and re-run.

Did This Fix Work in Your Case?

Quick signal helps us prioritize which fixes to verify and improve.

Prevention

  • Add a CI check that diffs key outputs after upgrades (OpenAPI schema snapshots, JSON payload shapes, CLI output).
  • Upgrade behind a canary and run integration tests against the canary before 100% rollout.
  • Add a TLS smoke test that performs a real handshake in CI (include CA bundle validation and hostname checks).
  • Alert on handshake failures by error string and endpoint to catch cert/CA changes quickly.

Version Compatibility Table

VersionStatus
1.25 Fixed

Related Issues

No related fixes found.

Sources

We don’t republish the full GitHub discussion text. Use the links above for context.